There is a very special bond between Cosoleto and San Rocco. The core of this deep faith lies in the holy sanctuary located in the village of Acquaro.
The church is an imposing structure that attracts many faithful especially in the feast days of the saint which take place on August 16 and November 1.

There is a legend linked to his birth that tells of a noblewoman from Montpellier, the San Rocco’s country of origin, who came to Cosoleto in search of peace and comfort, which she found in Acquaro. To give thanks, she decided to have a church erected in honor of San Rocco. The construction of the church dates back to a period between 1926 and 1932, and was commissioned by Monsignor Paolo Albera, Bishop of Mileto. Subsequently, it was consecrated a sanctuary on December 12, 1956 by decree of Bishop Vincenzo De Chiara.

There is also another legend that links Cosoleto to San Rocco and concerns the Statue of San Rocco. Shepherds made the statue, and then as soon as it was completed, it was transported to Sinopoli in accordance with the initial agreements with the buyer. However, the day after the statue was delivered, it was found once again at the place where it had been carved, that is, in Cosoleto, as if to testify the strong love of the saint for the country. Today, the statue of San Rocco still watches over the faithful, in the sanctuary of Acquaro. It is placed in a niche on the main altar from which, every year at the stroke of midnight on August 16, it is guided down to the center of the church thanks to a specially constructed ramp called a "farmiculara". An intensely spiritual event accompanied by prayers, songs, and applause from the faithful. The statue remains in place until November 1 when, at noon, it is returned to its rightful place in the niche overlooking the alter. These are the two dates in which the cult of San Rocco reaches its culmination. The sanctuary of San Rocco stands imposingly in the square thanks to its size and its elevated position at the end of a long staircase. Its exterior façade is characterized by an eclectic style, with a beautiful central rose window and is flanked by a bell tower on its right side. Inside the church there are three naves: two aisles and a central nave ending with a semicircular apse. Murals line the walls, some of which depict scenes from the life of San Rocco.